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Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit

The asymmetrically dividing yeast S. cerevisiae assembles a bipolar spindle well after establishing the future site of cell division (i.e., the bud neck) and the division axis (i.e., the mother-bud axis). A surveillance mechanism called spindle position checkpoint (SPOC) delays mitotic exit and cyto...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Scarfone, Ilaria, Venturetti, Marianna, Hotz, Manuel, Lengefeld, Jette, Barral, Yves, Piatti, Simonetta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450052/
https://ncbi.nlm.nih.gov/pubmed/25658911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004938
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