Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia

BACKGROUND: Inflammation due to remote pathogen exposure combined to hypoxia/ischemia (HI) is one of the most common causes of neonatal encephalopathy affecting at-term or near-term human newborn, which will consequently develop cerebral palsy. Within term-equivalent rat brains exposed to systemic l...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Savard, Alexandre, Brochu, Marie-Elsa, Chevin, Mathilde, Guiraut, Clémence, Grbic, Djordje, Sébire, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449972/
https://ncbi.nlm.nih.gov/pubmed/26025257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0330-8
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