Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4(+) T cells

Inflammatory CD4(+) T cell responses to self or commensal bacteria underlie the pathogenesis of autoimmunity and inflammatory bowel disease (IBD), respectively. While selection of self-specific T cells in the thymus limits responses to tissue antigens, the mechanisms that control selection of commen...

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Udgivet i:Science
Main Authors: Hepworth, Matthew R., Fung, Thomas C., Masur, Samuel H., Kelsen, Judith R., McConnell, Fiona M., Dubrot, Juan, Withers, David R., Hugues, Stephanie, Farrar, Michael A., Reith, Walter, Eberl, Gerard, Baldassano, Robert N., Laufer, Terri M., Elson, Charles O., Sonnenberg, Gregory F.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449822/
https://ncbi.nlm.nih.gov/pubmed/25908663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa4812
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