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Candida albicans Cas5, a Regulator of Cell Wall Integrity, Is Required for Virulence in Murine and Toll Mutant Fly Models

Candida albicans is the most common human fungal pathogen, yet the pathogenesis of C. albicans infection remains incompletely understood. We hypothesized that C. albicans has developed evolutionarily conserved mechanisms to invade disparate hosts and tested whether Toll mutant flies could serve as a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Chamilos, Georgios, Nobile, Clarissa J., Bruno, Vincent M., Lewis, Russell E., Mitchell, Aaron P., Kontoyiannis, Dimitrios P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449728/
https://ncbi.nlm.nih.gov/pubmed/19463063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599363
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