Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination

BACKGROUND: The discovery of malaria transmission-blocking compounds is seen as key to malaria elimination strategies and gametocyte-screening platforms are critical filters to identify active molecules. However, unlike asexual parasite assays measuring parasite proliferation, greater variability in...

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Detalles Bibliográficos
Publicado en:Malar J
Main Authors: Reader, Janette, Botha, Mariëtte, Theron, Anjo, Lauterbach, Sonja B, Rossouw, Claire, Engelbrecht, Dewaldt, Wepener, Melanie, Smit, Annél, Leroy, Didier, Mancama, Dalu, Coetzer, Theresa L, Birkholtz, Lyn-Marie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449569/
https://ncbi.nlm.nih.gov/pubmed/25994518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0718-z
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