Transmembrane complexes of DAP12 crystallized in lipid membranes provide insights into control of oligomerization in immunoreceptor assembly

The membrane-spanning α-helices of single-pass receptors play crucial roles in stabilizing oligomeric structures and transducing biochemical signals across the membrane. Probing intermolecular transmembrane interactions in single-pass receptors presents unique challenges, reflected in a gross underr...

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Publicat a:Cell Rep
Autors principals: Knoblich, Konstantin, Park, Soohyung, Lutfi, Mariam, Hag, Leonie van’t, Conn, Charlotte E., Seabrook, Shane A., Newman, Janet, Czabotar, Peter E., Im, Wonpil, Call, Matthew E., Call, Melissa J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449314/
https://ncbi.nlm.nih.gov/pubmed/25981043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.045
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