Low Affinity Binding Site Clusters Confer Hox Specificity and Regulatory Robustness

In animals, Hox transcription factors define regional identity in distinct anatomical domains. How Hox genes encode this specificity is a paradox, because different Hox proteins bind with high affinity in vitro to similar DNA sequences. Here, we demonstrate that the Hox protein Ultrabithorax (Ubx) i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell
Autors principals: Crocker, Justin, Abe, Namiko, Rinaldi, Lucrezia, McGregor, Alistair P., Frankel, Nicolás, Wang, Shu, Alsawadi, Ahmad, Valenti, Philippe, Plaza, Serge, Payre, François, Mann, Richard S., Stern, David L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449256/
https://ncbi.nlm.nih.gov/pubmed/25557079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.041
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars