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In vitro evidence for endocrine-disrupting chemical (EDC)'s inhibition of drug metabolism

BACKGROUND: Humans can be frequently exposed to Bisphenol A (BPA) via multiple sources, and babies are considered to be the most sensitive group to exposure of BPA. AIMS: To investigate the inhibition potential of BPA towards human liver microsomes (HLMs)-catalyzed zidovudine (AZT) glucuronidation....

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Publicado en:Afr Health Sci
Main Authors: Li, Wei-Ping, Wang, Yu-Feng, Gao, Jian, Yu, Ming-Lian, Yu, Yan-Yang, Yao, Yuan-Qing
Formato: Artigo
Idioma:Inglês
Publicado: Makerere Medical School 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449052/
https://ncbi.nlm.nih.gov/pubmed/26060477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4314/ahs.v14i1.28
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