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Re-examination of regulatory opinions in Europe: possible contribution for the approval of the first gene therapy product Glybera

The first commercially approved human gene therapy in the Western world is Glybera (alipogene tiparvovec), which is an adenoassociated viral vector encoding the lipoprotein lipase gene. Glybera was recommended for marketing authorization by the European Medicines Agency in 2012. The European Medicin...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Watanabe, Natsumi, Yano, Kazuo, Tsuyuki, Kenichiro, Okano, Teruo, Yamato, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449026/
https://ncbi.nlm.nih.gov/pubmed/26052534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.66
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