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THE CANNABINOID RECEPTOR ANTAGONIST AM251 INCREASES PARAOXON AND CHLORPYRIFOS OXON TOXICITY IN RATS

Organophosphorus anticholinesterases (OPs) elicit acute toxicity by inhibiting acetylcholinesterase (AChE), leading to acetylcholine accumulation and overstimulation of cholinergic receptors. Endocannabinoids (eCBs, e.g., arachidonoyl ethanolamide [AEA] and 2-arachidonoyl glycerol [2-AG]) are neurom...

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Bibliografiske detaljer
Udgivet i:Neurotoxicology
Main Authors: Liu, Jing, Pope, Carey
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448943/
https://ncbi.nlm.nih.gov/pubmed/25447325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.11.001
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