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Chromosomes progress to metaphase in multiple discrete steps via global compaction/expansion cycles

Mammalian mitotic chromosome morphogenesis was analyzed by 4D live cell and snapshot deconvolution fluorescence imaging. Prophase chromosomes, whose organization was previously unknown, are revealed to comprise co-oriented sister linear loop arrays displayed along a single, peripheral, regularly-kin...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Liang, Zhangyi, Zickler, Denise, Prentiss, Mara, Chang, Frederick S., Witz, Guillaume, Maeshima, Kazuhiro, Kleckner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448932/
https://ncbi.nlm.nih.gov/pubmed/26000485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.030
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