Copper-promoted synthesis of 1,4-benzodiazepinones via alkene diamination

A new method for the synthesis of 2-aminomethyl functionalized 1,4-benzodiazepin-5-ones is presented. The benzodiazepine core is well-known to interact with biological receptors and many pharmaceutical drugs are derived from this structure. The alkene diamination strategy is employed for the first t...

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Detaylı Bibliyografya
Yayımlandı:Tetrahedron Lett
Asıl Yazarlar: Karyakarte, Shuklendu D., Sequeira, Fatima C., Zibreg, Garrick H., Huang, Guoqing, Matthew, Josiah P., Ferreira, Marina M. M., Chemler, Sherry R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448762/
https://ncbi.nlm.nih.gov/pubmed/26034340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.01.171
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