Optically Triggered Immune Response through Photocaged Oligonucleotides

Bacterial and viral CpG oligonculeotides are unmethylated cytosine-phosphate-guanosine dinucleotide sequences and trigger an innate immune response through activation of the toll-like receptor 9 (TLR9). We have developed synthetic photocaged CpGs via site-specific incorporation of nitropiperonyloxym...

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Bibliographic Details
Published in:Tetrahedron Lett
Main Authors: Govan, Jeane M., Young, Douglas D., Lively, Mark O., Deiters, Alexander
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448726/
https://ncbi.nlm.nih.gov/pubmed/26034339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.01.165
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