The Microphthalmia Transcription Factor (Mitf) Controls Expression of the Ocular Albinism Type 1 Gene: Link between Melanin Synthesis and Melanosome Biogenesis

Melanogenesis is the process that regulates skin and eye pigmentation. Albinism, a genetic disease causing pigmentation defects and visual disorders, is caused by mutations in genes controlling either melanin synthesis or melanosome biogenesis. Here we show that a common transcriptional control regu...

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Detalhes bibliográficos
Main Authors: Vetrini, Francesco, Auricchio, Alberto, Du, Jinyan, Angeletti, Barbara, Fisher, David E., Ballabio, Andrea, Marigo, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444869/
https://ncbi.nlm.nih.gov/pubmed/15254223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6550-6559.2004
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