Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing

Although physiological steroid levels are often pulsatile (ultradian), the genomic effects of this pulsatility are poorly understood. By utilizing glucocorticoid receptor (GR) signaling as a model system, we uncovered striking spatiotemporal relationships between receptor loading, lifetimes of the D...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Stavreva, Diana A., Coulon, Antoine, Baek, Songjoon, Sung, Myong-Hee, John, Sam, Stixova, Lenka, Tesikova, Martina, Hakim, Ofir, Miranda, Tina, Hawkins, Mary, Stamatoyannopoulos, John A., Chow, Carson C., Hager, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448681/
https://ncbi.nlm.nih.gov/pubmed/25677181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.184168.114
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