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Drosophila C-Terminal Src Kinase Negatively Regulates Organ Growth and Cell Proliferation through Inhibition of the Src, Jun N-Terminal Kinase, and STAT Pathways

Src family kinases regulate multiple cellular processes including proliferation and oncogenesis. C-terminal Src kinase (Csk) encodes a critical negative regulator of Src family kinases. We demonstrate that the Drosophila melanogaster Csk ortholog, dCsk, functions as a tumor suppressor: dCsk mutants...

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Bibliografski detalji
Glavni autori: Read, Renee D., Bach, Erika A., Cagan, Ross L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC444864/
https://ncbi.nlm.nih.gov/pubmed/15254235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.15.6676-6689.2004
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