Functional Complementation of Human Centromere Protein A (CENP-A) by Cse4p from Saccharomyces cerevisiae

We have employed a novel in vivo approach to study the structure and function of the eukaryotic kinetochore multiprotein complex. RNA interference (RNAi) was used to block the synthesis of centromere protein A (CENP-A) and Clip-170 in human cells. By coexpression, homologous kinetochore proteins fro...

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Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Wieland, Gerhard, Orthaus, Sandra, Ohndorf, Sabine, Diekmann, Stephan, Hemmerich, Peter
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2004
Sujets:	DNA Dynamics and Chromosome Structure
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.15.6620-6630.2004
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