Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment

BACKGROUND: The mechanisms allowing residual multiple myeloma (MM) cells to persist after bortezomib (Bz) treatment remain unclear. We hypothesized that studying the biology of bortezomib-surviving cells may reveal markers to identify these cells and survival signals to target and kill residual MM c...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Adomako, Alfred, Calvo, Veronica, Biran, Noa, Osman, Keren, Chari, Ajai, Paton, James C, Paton, Adrienne W, Moore, Kateri, Schewe, Denis M, Aguirre-Ghiso, Julio A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448210/
https://ncbi.nlm.nih.gov/pubmed/26025442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1460-1
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