WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling

WISP1/CCN4 (hereafter referred to as WISP1), a member of the CCN family, is found in mineralized tissues and is produced by osteoblasts and their precursors. In this study, Wisp1-deficient (Wisp1(−/−)) mice were generated. Using dual-energy x-ray absorptiometry, we showed that by 3 months, the total...

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Vydáno v:J Biol Chem
Hlavní autoři: Maeda, Azusa, Ono, Mitsuaki, Holmbeck, Kenn, Li, Li, Kilts, Tina M., Kram, Vardit, Noonan, Megan L., Yoshioka, Yuya, McNerny, Erin M. B., Tantillo, Margaret A., Kohn, David H., Lyons, Karen M., Robey, Pamela G., Young, Marian F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447973/
https://ncbi.nlm.nih.gov/pubmed/25864198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628818
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