Crucial Roles of Single Residues in Binding Affinity, Specificity, and Promiscuity in the Cellulosomal Cohesin-Dockerin Interface

Interactions between cohesin and dockerin modules play a crucial role in the assembly of multienzyme cellulosome complexes. Although intraspecies cohesin and dockerin modules bind in general with high affinity but indiscriminately, cross-species binding is rare. Here, we combined ELISA-based experim...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Slutzki, Michal, Reshef, Dan, Barak, Yoav, Haimovitz, Rachel, Rotem-Bamberger, Shahar, Lamed, Raphael, Bayer, Edward A., Schueler-Furman, Ora
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447945/
https://ncbi.nlm.nih.gov/pubmed/25833947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.651208
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