IgH-V(D)J NGS-MRD measurement pre- and early post-allotransplant defines very low- and very high-risk ALL patients

Positive detection of minimal residual disease (MRD) by multichannel flow cytometry (MFC) prior to hematopoietic cell transplantation (HCT) of patients with acute lymphoblastic leukemia (ALL) identifies patients at high risk for relapse, but many pre-HCT MFC-MRD negative patients also relapse, and t...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Pulsipher, Michael A., Carlson, Chris, Langholz, Bryan, Wall, Donna A., Schultz, Kirk R., Bunin, Nancy, Kirsch, Ilan, Gastier-Foster, Julie M., Borowitz, Michael, Desmarais, Cindy, Williamson, David, Kalos, Michael, Grupp, Stephan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447864/
https://ncbi.nlm.nih.gov/pubmed/25862561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-12-615757
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