Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial

Background. Acyclovir (ACV), a highly specific anti-herpetic drug, acts as a DNA chain terminator for several human herpesviruses (HHVs), including HHV-2 (HSV-2), a common human immunodeficiency virus (HIV)-1 co-pathogen. Several trials demonstrated that HSV-2 suppressive therapy using ACV or its pr...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Vanpouille, Christophe, Lisco, Andrea, Grivel, Jean-Charles, Bassit, Leda C., Kauffman, Robert C., Sanchez, Jorge, Schinazi, Raymond F., Lederman, Michael M., Rodriguez, Benigno, Margolis, Leonid
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
HIV/AIDS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447783/
https://ncbi.nlm.nih.gov/pubmed/25740794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ172
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