Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development

Sine oculis-related homeobox 3 (SIX3) and SIX6, 2 closely related homeodomain transcription factors, are involved in development of the mammalian neuroendocrine system and mutations of Six6 adversely affect fertility in mice. We show that both small interfering RNA knockdown in gonadotrope cell line...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Xie, Huimin, Hoffmann, Hanne M., Meadows, Jason D., Mayo, Susan L., Trang, Crystal, Leming, Sunamita S., Maruggi, Chiara, Davis, Shannon W., Larder, Rachel, Mellon, Pamela L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447639/
https://ncbi.nlm.nih.gov/pubmed/25915183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1279
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