Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae

Functionally constrained genes are ideal insecticide targets because disruption is often fatal, and resistance mutations are typically costly. Synaptic acetylcholinesterase (AChE) is an essential neurotransmission enzyme targeted by insecticides used increasingly in malaria control. In Anopheles and...

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Detalhes bibliográficos
Publicado no:Mol Ecol
Main Authors: Weetman, David, Mitchell, Sara N, Wilding, Craig S, Birks, Daniel P, Yawson, Alexander E, Essandoh, John, Mawejje, Henry D, Djogbenou, Luc S, Steen, Keith, Rippon, Emily J, Clarkson, Christopher S, Field, Stuart G, Rigden, Daniel J, Donnelly, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447564/
https://ncbi.nlm.nih.gov/pubmed/25865270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mec.13197
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