Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae

Functionally constrained genes are ideal insecticide targets because disruption is often fatal, and resistance mutations are typically costly. Synaptic acetylcholinesterase (AChE) is an essential neurotransmission enzyme targeted by insecticides used increasingly in malaria control. In Anopheles and...

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Dades bibliogràfiques
Publicat a:Mol Ecol
Autors principals: Weetman, David, Mitchell, Sara N, Wilding, Craig S, Birks, Daniel P, Yawson, Alexander E, Essandoh, John, Mawejje, Henry D, Djogbenou, Luc S, Steen, Keith, Rippon, Emily J, Clarkson, Christopher S, Field, Stuart G, Rigden, Daniel J, Donnelly, Martin J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447564/
https://ncbi.nlm.nih.gov/pubmed/25865270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mec.13197
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