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Chronic Myeloid Leukemia: Advances in Understanding Disease Biology and Mechanisms of Resistance to Tyrosine Kinase Inhibitors

The successful implementation of tyrosine kinase inhibitors (TKIs) for the treatment of chronic myeloid leukemia (CML) remains a flagship for molecularly targeted therapy in cancer. This focused review highlights critical elements of the underlying biology of CML and provides a summary of the molecu...

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Detalhes bibliográficos
Publicado no:Curr Hematol Malig Rep
Main Authors: Eide, Christopher A., O’Hare, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447524/
https://ncbi.nlm.nih.gov/pubmed/25700679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11899-015-0248-3
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