Abbreviated Exposure to Hypoxia Is Sufficient to Induce CNS Dysmyelination, Modulate Spinal Motor Neuron Composition, and Impair Motor Development in Neonatal Mice

Neonatal white matter injury (nWMI) is an increasingly common cause of cerebral palsy that results predominantly from hypoxic injury to progenitor cells including those of the oligodendrocyte lineage. Existing mouse models of nWMI utilize prolonged periods of hypoxia during the neonatal period, requ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Watzlawik, Jens O., Kahoud, Robert J., O’Toole, Ryan J., White, Katherine A. M., Ogden, Alyssa R., Painter, Meghan M., Wootla, Bharath, Papke, Louisa M., Denic, Aleksandar, Weimer, Jill M., Carey, William A., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447462/
https://ncbi.nlm.nih.gov/pubmed/26020269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128007
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