Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types

Monoclonal gammopathy of undetermined significance (MGUS) is the requisite precursor to multiple myeloma (MM), a malignancy of antibody-producing plasma B-cells. The genetic basis of MGUS and its progression to MM remains poorly understood. C57BL/KaLwRij (KaLwRij) is a spontaneously-derived inbred m...

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Publicat a:PLoS One
Autors principals: Amend, Sarah R., Wilson, William C., Chu, Liang, Lu, Lan, Liu, Pengyuan, Serie, Daniel, Su, Xinming, Xu, Yalin, Wang, Dingyan, Gramolini, Anthony, Wen, Xiao-Yan, O’Neal, Julie, Hurchla, Michelle, Vachon, Celine M., Colditz, Graham, Vij, Ravi, Weilbaecher, Katherine N., Tomasson, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447437/
https://ncbi.nlm.nih.gov/pubmed/26020268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127828
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