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In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA

DnaA, the replication initiation protein in bacteria, is an AAA+ ATPase that binds and hydrolyzes ATP and exists in a heterogeneous population of ATP-DnaA and ADP-DnaA. DnaA binds cooperatively to the origin of replication and several other chromosomal regions, and functions as a transcription facto...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Smith, Janet L., Grossman, Alan D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447404/
https://ncbi.nlm.nih.gov/pubmed/26020636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005258
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