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Design Space Development for the Extraction Process of Danhong Injection Using a Monte Carlo Simulation Method

A design space approach was applied to optimize the extraction process of Danhong injection. Dry matter yield and the yields of five active ingredients were selected as process critical quality attributes (CQAs). Extraction number, extraction time, and the mass ratio of water and material (W/M ratio...

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Vydáno v:PLoS One
Hlavní autoři: Gong, Xingchu, Li, Yao, Chen, Huali, Qu, Haibin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447344/
https://ncbi.nlm.nih.gov/pubmed/26020778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128236
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