Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cells

Leukemic cells disrupt normal patterns of blood cell formation, but little is understood about the mechanism. We investigated if leukemic cells alter functions of normal hematopoietic stem and progenitor cells. Exposure to chronic myelogenous leukemia (CML) caused normal mouse hematopoietic progenit...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Welner, Robert S., Amabile, Giovanni, Bararia, Deepak, Czibere, Akos, Yang, Henry, Zhang, Hong, Pontes, Lorena Lobo De Figueiredo, Ye, Min, Levantini, Elena, Ruscio, Annalisa Di, Martinelli, Giovanni, Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447336/
https://ncbi.nlm.nih.gov/pubmed/25965572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.04.004
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