Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells

BACKGROUND: Mechanical ventilation plays a central role in the injury of premature lungs. However, the mechanisms by which mechanical signals trigger an inflammatory cascade to promote lung injury are not well-characterized. Transient receptor potential vanilloid 4 (TRPV4), a calcium-permeable mecha...

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Vydáno v:Respir Res
Hlavní autoři: Nayak, Pritha S., Wang, Yulian, Najrana, Tanbir, Priolo, Lauren M., Rios, Mayra, Shaw, Sunil K., Sanchez-Esteban, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446903/
https://ncbi.nlm.nih.gov/pubmed/26006045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0224-4
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