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Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein.

Carbapenems such as imipenem are extended-spectrum beta-lactam antibiotics, which are not hydrolyzed by the beta-lactamases commonly found in Enterobacteriaceae. Here we report a gene encoding a carbapenemase, which was cloned from the chromosome of a clinical isolate of Enterobacter cloacae, strain...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Naas, T, Nordmann, P
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44468/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7693
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