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Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration

Skeletal muscle satellite cells (SCs) are Pax7(+) myogenic stem cells that reside between the basal lamina and the plasmalemma of the myofiber. In mature muscles, SCs are typically quiescent, but can be activated in response to muscle injury. Depending on the magnitude of tissue trauma, SCs may divi...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Yablonka-Reuveni, Zipora, Danoviz, Maria E., Phelps, Michael, Stuelsatz, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446549/
https://ncbi.nlm.nih.gov/pubmed/26074812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00085
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