Single-Round Patterned DNA Library Microarray Aptamer Lead Identification

A method for identifying an aptamer in a single round was developed using custom DNA microarrays containing computationally derived patterned libraries incorporating no information on the sequences of previously reported thrombin binding aptamers. The DNA library was specifically designed to increas...

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Veröffentlicht in:J Anal Methods Chem
Hauptverfasser: Martin, Jennifer A., Mirau, Peter A., Chushak, Yaroslav, Chávez, Jorge L., Naik, Rajesh R., Hagen, Joshua A., Kelley-Loughnane, Nancy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446497/
https://ncbi.nlm.nih.gov/pubmed/26075138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/137489
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