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Effects of Rate of Infusion and Probenecid on Serum Levels, Renal Excretion, and Tolerance of Intravenous Doses of Cefoxitin in Humans: Comparison with Cephalothin

Using a randomized crossover design, 1-g intravenous doses of cephalothin and cefoxitin, a cephalosporinase-resistant cephamycin, were infused into 12 normal adult males over periods of 120, 30, and 3 min, the last with and without prior intravenous infusions of probenecid (1 g). Mean peak serum con...

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Detalhes bibliográficos
Main Authors: Goodwin, C. Stewart, Raftery, E. B., Goldberg, A. D., Skeggs, H., Till, A. E., Martin, C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444649/
https://ncbi.nlm.nih.gov/pubmed/15830485
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