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5-Fluorocytosine and Amphotericin B in Bronchial Secretions

The penetration into and clearance from bronchial secretions of 5-fluorocytosine and amphotericin B were studied in a dog model. After a single intravenous dose of 35 mg/kg, 5-fluorocytosine intrabronchial concentrations were greater than the minimal inhibitory concentration for 80 to 90% of Candida...

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Detalhes bibliográficos
Main Authors: Pennington, James E., Block, Edward R., Reynolds, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444645/
https://ncbi.nlm.nih.gov/pubmed/15830481
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