A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes

The chromatin remodeling complex NoRC, comprising the subunits SNF2h and TIP5/BAZ2A, mediates heterochromatin formation at major clusters of repetitive elements, including rRNA genes, centromeres and telomeres. Association with chromatin requires the interaction of the TAM (TIP5/ARBP/MBD) domain of...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Anosova, Irina, Melnik, Svitlana, Tripsianes, Konstantinos, Kateb, Fatiha, Grummt, Ingrid, Sattler, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446428/
https://ncbi.nlm.nih.gov/pubmed/25916849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv365
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