Normal Free Interleukin-18 (IL-18) Plasma Levels in Dengue Virus Infection and the Need To Measure Both Total IL-18 and IL-18 Binding Protein Levels

Activated monocytes/macrophages and T lymphocytes that produce a cytokine storm are assumed to play a pivotal role in the pathogenesis of dengue. Interleukin-18 (IL-18) is a proinflammatory cytokine that is increased during dengue and known to induce gamma interferon (IFN-γ), which is crucial for de...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Vaccine Immunol
Hauptverfasser: Michels, Meta, de Mast, Quirijn, Netea, Mihai G., Joosten, Leo A., Dinarello, Charles A., Rudiman, Pandji I. F., Sinarta, Sylvia, Wisaksana, Rudi, Alisjahbana, Bachti, van der Ven, André J. A. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Clinical Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446409/
https://ncbi.nlm.nih.gov/pubmed/25878254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00147-15
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