Protective Efficacy of the Conserved NP, PB1, and M1 Proteins as Immunogens in DNA- and Vaccinia Virus-Based Universal Influenza A Virus Vaccines in Mice

The conventional hemagglutinin (HA)- and neuraminidase (NA)-based influenza vaccines need to be updated most years and are ineffective if the glycoprotein HA of the vaccine strains is a mismatch with that of the epidemic strain. Universal vaccines targeting conserved viral components might provide c...

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Dettagli Bibliografici
Pubblicato in:Clin Vaccine Immunol
Autori principali: Wang, Wenling, Li, Renqing, Deng, Yao, Lu, Ning, Chen, Hong, Meng, Xin, Wang, Wen, Wang, Xiuping, Yan, Kexia, Qi, Xiangrong, Zhang, Xiangmin, Xin, Wei, Lu, Zhenhua, Li, Xueren, Bian, Tao, Gao, Yingying, Tan, Wenjie, Ruan, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446406/
https://ncbi.nlm.nih.gov/pubmed/25834017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00091-15
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