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Cefoxitin, a Semisynthetic Cephamycin Antibiotic: Antibacterial Spectrum and Resistance to Hydrolysis by Gram-Negative Beta-Lactamases

The in vitro activity of cefoxitin, 3-carbamolyloxymethyl-7-α-methoxy-7[2-(2-thienyl)acetamido]-3-cephem-4-carboyxlic acid, was investigated. Activity against gram-positive organisms was less than that of cephalothin and cephloridine. It was highly active against gram-negative bacilli, with activity...

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Bibliographic Details
Main Author: Neu, Harold C.
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC444623/
https://ncbi.nlm.nih.gov/pubmed/15828188
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