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Deformability in the Cleavage Site of Primary MicroRNA is Not Sensed by the Double-Stranded RNA Binding Domains in the Microprocessor Component DGCR8

The prevalence of double-stranded RNA (dsRNA) in eukaryotic cells has only recently been appreciated. Of interest here, RNA silencing begins with dsRNA substrates that are bound by the double-stranded RNA binding domains (dsRBDs) of their processing proteins. Specifically, processing of microRNA (mi...

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Bibliografiska uppgifter
I publikationen:Proteins
Huvudupphovsmän: Quarles, Kaycee A., Chadalavada, Durga, Showalter, Scott A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446130/
https://ncbi.nlm.nih.gov/pubmed/25851436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24810
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