Full UPF3B function is critical for neuronal differentiation of neural stem cells

BACKGROUND: Mutation in the UPF3B gene on chromosome X is implicated in neurodevelopmental disorders including X-linked intellectual disability, autism and schizophrenia. The protein UPF3B is involved in the nonsense-mediated mRNA decay pathway (NMD) that controls mRNA stability and functions in the...

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Pubblicato in:Mol Brain
Autori principali: Alrahbeni, Tahani, Sartor, Francesca, Anderson, Jihan, Miedzybrodzka, Zosia, McCaig, Colin, Müller, Berndt
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445987/
https://ncbi.nlm.nih.gov/pubmed/26012578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0122-1
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