The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer death globally and new biomarkers and treatments are severely needed. METHODS: Here, we employed HCT116 and LoVo human CRC cells made resistant to either SN38 or oxaliplatin, to investigate whether altered expression of the high affini...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Pedraz-Cuesta, Elena, Christensen, Sandra, Jensen, Anders A., Jensen, Niels Frank, Bunch, Lennart, Romer, Maria Unni, Brünner, Nils, Stenvang, Jan, Pedersen, Stine Falsig
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445981/
https://ncbi.nlm.nih.gov/pubmed/25981639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1405-8
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