Functional bottlenecks for generation of HIV-1 intersubtype Env recombinants

BACKGROUND: Intersubtype recombination is a powerful driving force for HIV evolution, impacting both HIV-1 diversity within an infected individual and within the global epidemic. This study examines if viral protein function/fitness is the major constraint shaping selection of recombination hotspots...

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Gepubliceerd in:Retrovirology
Hoofdauteurs: Bagaya, Bernard S., Vega, José F., Tian, Meijuan, Nickel, Gabrielle C., Li, Yuejin, Krebs, Kendall C., Arts, Eric J., Gao, Yong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445978/
https://ncbi.nlm.nih.gov/pubmed/25997955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0170-8
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