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Characterization of the effect of oral rofecoxib treatment on PTZ-induced acute seizures and kindling
PURPOSE: The goal of this study was to determine whether prophylatic prandial administration of rofecoxib, a selective cyclooxygenase (COX)-2 inhibitor, could alter seizure generation, kindling acquisition and/or kindling maintenance in the mouse pentylenetetrazole (PTZ) epilepsy model. METHODS: Mal...
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| Publicado no: | Epilepsia |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445939/ https://ncbi.nlm.nih.gov/pubmed/21219314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02889.x |
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