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Characterization of the effect of oral rofecoxib treatment on PTZ-induced acute seizures and kindling

PURPOSE: The goal of this study was to determine whether prophylatic prandial administration of rofecoxib, a selective cyclooxygenase (COX)-2 inhibitor, could alter seizure generation, kindling acquisition and/or kindling maintenance in the mouse pentylenetetrazole (PTZ) epilepsy model. METHODS: Mal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Epilepsia
Egile Nagusiak: Claycomb, Robert J, Hewett, Sandra J, Hewett, James A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445939/
https://ncbi.nlm.nih.gov/pubmed/21219314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02889.x
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