Slit/Robo pathway: a promising therapeutic target for cancer

Axon guidance molecules, slit glycoprotein (Slit) and Roundabout receptor (Robo), have implications in the regulation of physiological processes. Recent studies indicate that Slit and Robo also have important roles in tumorigenesis, cancer progression and metastasis. The Slit/Robo pathway can be con...

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Bibliografiske detaljer
Udgivet i:Drug Discov Today
Main Authors: Gara, Rishi K., Kumari, Sonam, Ganju, Aditya, Yallapu, Murali M., Jaggi, Meena, Chauhan, Subhash C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445861/
https://ncbi.nlm.nih.gov/pubmed/25245168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.09.008
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