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Use of the 295- to 300-Nanometer Circular Dichroism Trough of Ribonucleic Acid to Study Helix Winding: Effect of Acridine Orange

Acridine orange decreases the amplitude of the 295-nm circular dichroism (CD) trough of ribosomal ribonucleic acid (rRNA) where the trough has been related to coil character. Since acridine orange is known from earlier work to intercalate between base pairs of nucleic acids, causing an unwinding of...

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Detalhes bibliográficos
Main Authors: Hoener, Betty-Ann, Sokoloski, Theodore D., Mitscher, Lester A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444576/
https://ncbi.nlm.nih.gov/pubmed/4791307
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