The relative contribution of common and rare genetic variants to ADHD

Attention deficit hyperactivity disorder (ADHD) is highly heritable. Genome-wide molecular studies show an increased burden of large, rare copy-number variants (CNVs) in children with ADHD compared with controls. Recent polygenic risk score analyses have also shown that en masse common variants are...

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Udgivet i:Transl Psychiatry
Main Authors: Martin, J, O'Donovan, M C, Thapar, A, Langley, K, Williams, N
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445754/
https://ncbi.nlm.nih.gov/pubmed/25668434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.5
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