Sorafenib prevents liver fibrosis in a non-alcoholic steatohepatitis (NASH) rodent model

Liver fibrosis occurring as an outcome of non-alcoholic steatohepatitis (NASH) can precede the development of cirrhosis. We investigated the effects of sorafenib in preventing liver fibrosis in a rodent model of NASH. Adult Sprague-Dawley rats were fed a choline-deficient high-fat diet and exposed t...

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Dades bibliogràfiques
Publicat a:Braz J Med Biol Res
Autors principals: Stefano, J.T., Pereira, I.V.A., Torres, M.M., Bida, P.M., Coelho, A.M.M., Xerfan, M.P., Cogliati, B., Barbeiro, D.F., Mazo, D.F.C., Kubrusly, M.S., D'Albuquerque, L.A.C., Souza, H.P., Carrilho, F.J., Oliveira, C.P.
Format: Artigo
Idioma:Inglês
Publicat: Associação Brasileira de Divulgação Científica 2015
Matèries:
Biomedical Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445663/
https://ncbi.nlm.nih.gov/pubmed/25714891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20143962
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