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Implantation of rAAV5-IGF-I Transduced Autologous Chondrocytes Improves Cartilage Repair in Full-thickness Defects in the Equine Model

Cartilage injury often precipitates osteoarthritis which has driven research to bolster repair in cartilage impact damage. Autologous chondrocytes transduced with rAAV5-IGF-I were evaluated in chondral defects in a well-established large animal model. Cartilage was harvested from the talus of 24 hor...

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Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Ortved, Kyla F, Begum, Laila, Mohammed, Hussni O, Nixon, Alan J
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445609/
https://ncbi.nlm.nih.gov/pubmed/25311491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.198
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